Pergoveris 300 Iu/ 150 Iu, Pergoveris 450 Iu/ 225 Iu And Pergoveris 900 Iu/ 450 Iu 300 IU/150 IU, 450 IU/ 225 IU, 900 IU/ 450 IU Solution for Injection
PDF Leaflet Revision Date: 10 August 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Stimulation of follicular development in women with severe LH and FSH deficiency.
Dosage (summary)
Start with 150 IU r-hFSH/75 IU r-hLH daily, adjust as needed.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not indicated during pregnancy or breastfeeding.
Key Drug Interactions
- Concomitant use with licensed follitropin alfa preparations
Contraindications
- Hypersensitivity to active substances
- Tumours of hypothalamus/pituitary
- Ovarian enlargement/cysts of unknown origin
- Gynaecological haemorrhages of unknown origin
- Ovarian, uterine or mammary carcinoma
- Primary ovarian failure
- Malformations of sexual organs incompatible with pregnancy
Common side effects
- Headache
- Ovarian cysts
- Injection site reactions
- Mild to moderate OHSS
Counselling Points
- Monitor for signs of OHSS
- Discuss risks of multiple pregnancies
- Ensure proper training for self-administration
Serious warnings
- Risk of ovarian hyperstimulation syndrome (OHSS)
- Monitor for thromboembolic events
- Potential for multiple pregnancies
Important Disclaimer
The Pergoveris 300 Iu/ 150 Iu, Pergoveris 450 Iu/ 225 Iu And Pergoveris 900 Iu/ 450 Iu 300 IU/150 IU, 450 IU/ 225 IU, 900 IU/ 450 IU Solution for Injection professional information leaflet below is the property of Merck and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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