Cholstyq 0,5 mg, 2,5 mg Solution for injection
Clinical Summary
Quick overview from the medicine insert
Indication
Reversal of residual non-depolarising neuromuscular block.
Dosage (summary)
Adults: 1-2 ml IV over 10-30 seconds; repeat if needed. Total doses >2 ml not recommended.
Onset of Action / Duration
Onset: 1 min, Duration: Not specified.
Special Populations
- Elderly
- Renal impairment
- Asthma
- Cardiac conditions
- Epilepsy
- Myasthenia gravis
Pregnancy & Breastfeeding
Caution in pregnancy; may induce uterine irritability. Monitor breastfeeding infants.
Key Drug Interactions
- Suxamethonium
- MAOIs
- Aminoglycosides
- Beta-blockers
- Antidysrhythmics
Contraindications
- Hypersensitivity to active substances
- Mechanical obstruction of GI or urinary tracts
- Concomitant use with depolarising muscle relaxants
Common side effects
- Bradycardia
- Dizziness
- Dry mouth
- Nausea
- Blurred vision
Counselling Points
- Monitor for signs of overdose
- Avoid driving if vision is affected
- Report any severe allergic reactions
Serious warnings
- Caution in patients with asthma or severe bradycardia
- Risk of cholinergic crisis in myasthenia gravis
- Potential for ventricular dysrhythmias during inhalation anaesthesia
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