Aprovel 75mg, 150mg or 300mg Tablet
Clinical Summary
Quick overview from the medicine insert
Indication
Management of hypertension and nephropathy in patients with type 2 diabetes mellitus.
Dosage (summary)
Initial dose: 150 mg once daily; Maintenance dose: 150-300 mg once daily.
Onset of Action / Duration
Antihypertensive effect typically observed within 1-2 weeks of initiation.
Special Populations
- Elderly patients
- Patients with renal impairment
- Patients with hepatic impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy; contraindicated in the second and third trimesters. Use with caution during lactation.
Key Drug Interactions
- Potassium-sparing diuretics may increase the risk of hyperkalemia.
- NSAIDs may reduce the antihypertensive effect.
- Other antihypertensive agents may have additive effects.
Contraindications
- Hypersensitivity to irbesartan or any component of the formulation.
- Pregnancy (especially in the second and third trimesters).
- Severe renal impairment (GFR < 15 mL/min).
Common side effects
- Dizziness
- Fatigue
- Hypotension
- Hyperkalemia
- Renal impairment
Counselling Points
- Take the medication at the same time each day.
- Monitor blood pressure regularly.
- Report any signs of swelling, difficulty breathing, or persistent cough.
- Avoid potassium supplements unless directed by a healthcare provider.
Serious warnings
- Use with caution in patients with renal artery stenosis.
- Monitor renal function periodically.
- Discontinue if angioedema occurs.
Important Disclaimer
The Aprovel 75mg, 150mg or 300mg Tablet professional information leaflet below is the property of Sanofi-Aventis and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
Healthcare Professionals Only
This content is for registered healthcare professionals
Sign in or create a free account to read the full package insert.
Free for HPCSA-registered professionals. Powered by Medinsert.
