Campto 40mg / 2ml. 100mg / 5ml. 300mg / 15ml Infusion
PDF Leaflet Revision Date: 09 June 2016
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of advanced colorectal cancer.
Dosage (summary)
350 mg/mu00b2 IV every 3 weeks; 80 mg/mu00b2 weekly or 180 mg/mu00b2 every 2 weeks in combination with 5-FU/FA.
Onset of Action / Duration
Onset: 5 days for delayed diarrhea.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; may cause fetal harm.
Key Drug Interactions
- Azole antifungals
- St. John's Wort
- Antineoplastic agents
- Neuromuscular blocking agents
Contraindications
- Severe hypersensitivity
- Bilirubin > 1.5 x ULN
- Severe bone marrow failure
- Chronic inflammatory bowel disease
Common side effects
- Diarrhea
- Nausea
- Vomiting
- Neutropenia
- Anemia
Counselling Points
- Hydration and antidiarrheal therapy are crucial
- Avoid pregnancy during treatment
- Report any diarrhea immediately
Serious warnings
- Risk of severe diarrhea
- Monitor for febrile neutropenia
- Use in specialized units only
Important Disclaimer
The Campto 40mg / 2ml. 100mg / 5ml. 300mg / 15ml Infusion professional information leaflet below is the property of Pfizer and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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