Adco-Lamivudine 150 mg Tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of HIV-1 infection in combination with other antiretroviral agents.
Dosage (summary)
The recommended dose for adults and children over 14 years is 150 mg once daily. For children aged 3 months to 14 years, the dose is based on body weight.
Onset of Action / Duration
Onset of action is typically within 1-2 weeks, with maximum effect observed after several weeks of therapy.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly patients
Pregnancy & Breastfeeding
Lamivudine is classified as Category C. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is excreted in breast milk; caution should be exercised when administered to nursing mothers.
Key Drug Interactions
- Zidovudine may increase the risk of hematologic toxicity when used with Lamivudine.
- Concurrent use with other antiretroviral agents may require dosage adjustments.
Contraindications
- Hypersensitivity to Lamivudine or any component of the formulation.
- Severe hepatic impairment.
Common side effects
- Headache
- Nausea
- Fatigue
- Diarrhea
- Liver enzyme elevation
- Pancreatitis
Counselling Points
- Advise patients to take the medication exactly as prescribed.
- Inform patients about the importance of adherence to therapy to prevent resistance.
- Encourage patients to report any signs of liver problems, such as jaundice or dark urine.
Serious warnings
- Risk of lactic acidosis, especially in patients with liver disease.
- Monitor for signs of pancreatitis.
- Caution in patients with a history of hepatitis B virus infection.
Important Disclaimer
The Adco-Lamivudine 150 mg Tablets professional information leaflet below is the property of Adcock Ingram and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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