Synthroid 25 μg, 50 μg, 75 μg, 100 μg, Tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Hypothyroidism and pituitary TSH suppression.
Dosage (summary)
Adults: 1.7 u03bcg/kg/day; elderly: start at 25-50 u03bcg/day.
Onset of Action / Duration
Onset: 4-6 weeks, Duration: variable.
Special Populations
- Elderly
- Cardiovascular disease
- Pregnant women
Pregnancy & Breastfeeding
Safe in pregnancy; monitor TSH; minimal excretion in breast milk.
Key Drug Interactions
- Antacids
- Calcium supplements
- Warfarin
Contraindications
- Untreated thyrotoxicosis
- Acute myocardial infarction
- Adrenal insufficiency
Common side effects
- Hyperthyroidism symptoms
- Palpitations
- Weight loss
Counselling Points
- Take on an empty stomach
- Avoid certain foods that affect absorption
- Regular monitoring of TSH levels
Serious warnings
- Not for weight loss
- Monitor for cardiac symptoms
- Narrow therapeutic index
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