Dexithera 100 Μg/Ml 2 Ml, 100 Μg/Ml 4 Ml, 100 Μg/Ml 10 Ml 200 mg, 400 mg Concentrate for solution for infusion
PDF Leaflet Revision Date: 26 November 2024
Clinical Summary
Quick overview from the medicine insert
Indication
Sedation in ICU and monitored anaesthesia care.
Dosage (summary)
Loading: 1.0 mcg/kg over 10 mins; Maintenance: 0.2-0.7 mcg/kg/h.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not recommended in pregnancy; caution in breastfeeding.
Key Drug Interactions
- Anaesthetics
- Sedatives
- Opioids
Contraindications
- Hypersensitivity
- Sepsis
- Unstable trauma
- Hypovolaemia
- Heart block
- Uncontrolled cardiac failure
- Imminent hepatic failure
Common side effects
- Hypotension
- Bradycardia
- Nausea
- Dry mouth
- Hypoxia
Counselling Points
- Avoid driving for 24 hours post-sedation.
- Monitor for signs of bradycardia.
- Inform about potential sedation effects.
Serious warnings
- Serious bradycardia risk
- Continuous monitoring required
- Not for general anaesthesia
Important Disclaimer
The Dexithera 100 Μg/Ml 2 Ml, 100 Μg/Ml 4 Ml, 100 Μg/Ml 10 Ml 200 mg, 400 mg Concentrate for solution for infusion professional information leaflet below is the property of Abbott Laboratories South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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