Linezolid 600 Mg/300 Ml Aspen Solution For Infusion 600 mg/300 ml Solution for infusion
PDF Leaflet Revision Date: 10 November 2020
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of infections caused by susceptible Gram-positive bacteria.
Dosage (summary)
600 mg IV every 12 hours for adults; 10 mg/kg IV every 8 hours for children.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; likely excreted in breast milk.
Key Drug Interactions
- Monoamine oxidase inhibitors
- Serotonergic medications
- Sympathomimetics
Contraindications
- Hypersensitivity to linezolid
- Uncontrolled hypertension
- Carcinoid syndrome
Common side effects
- Headache
- Diarrhoea
- Nausea
- Vomiting
- Metallic taste
Counselling Points
- Monitor for visual impairment
- Avoid serotonergic drugs
- Report severe diarrhoea
Serious warnings
- Myelosuppression
- Peripheral neuropathy
- Optic neuropathy
- Lactic acidosis
Important Disclaimer
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