Annin Tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Hypertension and heart failure management; reduction of stroke risk in patients with hypertension and left ventricular hypertrophy.
Dosage (summary)
Initial dose is typically 50 mg once daily; may be adjusted based on blood pressure response, up to a maximum of 100 mg once daily.
Onset of Action / Duration
Antihypertensive effect usually observed within 1 week; maximum effect may take 3 to 6 weeks.
Special Populations
- Elderly patients
- Patients with renal impairment
- Patients with hepatic impairment
Pregnancy & Breastfeeding
Not recommended during pregnancy; contraindicated in the second and third trimesters. Use with caution during lactation.
Key Drug Interactions
- Potassium-sparing diuretics may increase the risk of hyperkalemia.
- Non-steroidal anti-inflammatory drugs (NSAIDs) may reduce the antihypertensive effect.
- Other antihypertensive agents may have additive effects.
Contraindications
- Hypersensitivity to losartan or any component of the formulation.
- Pregnancy (especially in the second and third trimesters).
- Severe hepatic impairment.
Common side effects
- Dizziness
- Fatigue
- Hypotension
- Hyperkalemia
- Renal impairment
Counselling Points
- Take the medication at the same time each day.
- Monitor blood pressure regularly.
- Report any signs of swelling, difficulty breathing, or severe dizziness.
- Avoid potassium supplements unless directed by a healthcare provider.
Serious warnings
- Use with caution in patients with renal artery stenosis.
- Monitor renal function periodically during treatment.
- Discontinue if angioedema occurs.
Important Disclaimer
The Annin Tablets professional information leaflet below is the property of Aurogen South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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