Recrom And Sterile Diluent For Recrom 50 mg Powder and Solvent for Solution for Injection/Infusion
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of multiple myeloma and ovarian cancer.
Dosage (summary)
8-30 mg/mu00b2 every 2-6 weeks; high doses 100-200 mg/mu00b2 with autologous bone marrow rescue.
Special Populations
- Renal impairment
- Elderly
- Children
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Nalidixic acid
- Ciclosporin
- Live vaccines
Contraindications
- Previous allergic reaction to melphalan
- Pregnancy
- Lactation
- Live vaccines
Common side effects
- Nausea
- Vomiting
- Thrombocytopenia
- Neutropenia
- Alopecia
Counselling Points
- Avoid pregnancy during treatment
- Monitor for bleeding signs
- Report any allergic reactions
Serious warnings
- Myelosuppression
- Leukaemogenic risk
- Mutagenicity
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