Bemetrazole 200. Bemetrazole 400 200 mg. 400 mg Tablets

Indication

Treatment of infections caused by anaerobic bacteria and certain protozoa, including bacterial vaginosis, trichomoniasis, and amebiasis.

Dosage (summary)

200 mg to 400 mg, taken orally, usually 2 to 3 times daily for 5 to 10 days depending on the infection being treated.

Onset of Action / Duration

Onset of action typically occurs within 1 to 2 hours after administration.

Special Populations

• Patients with liver impairment
• Elderly patients
• Patients with renal impairment

Pregnancy & Breastfeeding

Metronidazole is classified as Category B2 for pregnancy. It should be used during pregnancy only if clearly needed. It is excreted in breast milk; caution is advised when administering to nursing mothers.

Key Drug Interactions

• Alcohol: Concurrent use may cause a disulfiram-like reaction.
• Warfarin: May enhance the anticoagulant effect.
• Lithium: May increase lithium levels.

Contraindications

• Hypersensitivity to metronidazole or any component of the formulation.
• History of blood dyscrasias.
• First trimester of pregnancy (unless absolutely necessary).

Common side effects

• Nausea
• Headache
• Dizziness
• Diarrhea
• Metallic taste
• Abdominal cramps

Counselling Points

• Avoid alcohol during treatment and for at least 48 hours after completing therapy.
• Take the medication with food to minimize gastrointestinal upset.
• Complete the full course of therapy even if symptoms improve.