Avelon 400 mg/250 ml Tablets & Infusion
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of bacterial infections, including respiratory tract infections, skin and soft tissue infections, and intra-abdominal infections.
Dosage (summary)
The usual adult dosage is 400 mg once daily, administered orally or via infusion.
Onset of Action / Duration
Onset of action typically occurs within 1 to 2 hours after administration, with peak plasma concentrations reached within 1 to 2 hours.
Special Populations
- Elderly patients
- Patients with renal impairment
- Patients with hepatic impairment
Pregnancy & Breastfeeding
Moxifloxacin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not recommended during breastfeeding.
Key Drug Interactions
- Antacids containing magnesium or aluminum may reduce the absorption of Moxifloxacin.
- Warfarin may have increased anticoagulant effects when used with Moxifloxacin.
- Cationic agents (e.g., sucralfate, metal ions) may interfere with Moxifloxacin absorption.
Contraindications
- Hypersensitivity to Moxifloxacin or other fluoroquinolones
- History of tendon disorders related to fluoroquinolone use
- Patients with a history of myasthenia gravis
Common side effects
- Nausea
- Diarrhea
- Dizziness
- Headache
- Rash
- Tendon rupture
Counselling Points
- Take the medication as prescribed, at the same time each day.
- Avoid taking with dairy products or calcium-fortified juices.
- Report any signs of tendon pain or swelling immediately.
- Stay hydrated and maintain adequate fluid intake.
- Inform healthcare providers of any other medications being taken.
Serious warnings
- May cause QT interval prolongation; use with caution in patients with known cardiac conditions.
- Risk of Clostridium difficile-associated diarrhea.
- Use with caution in patients with a history of seizures.
Important Disclaimer
The Avelon 400 mg/250 ml Tablets & Infusion professional information leaflet below is the property of Bayer and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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