Aleve 220 mg Tablets.

Indication

Relief of mild to moderate pain, including headache, dental pain, menstrual cramps, muscle aches, and pain from arthritis.

Dosage (summary)

The recommended dose for adults is 220 mg every 8 to 12 hours as needed. Do not exceed 660 mg in a 24-hour period.

Onset of Action / Duration

Pain relief typically begins within 30 minutes to 1 hour after administration.

Special Populations

• Elderly patients may require dose adjustments due to increased risk of adverse effects.
• Patients with renal impairment should use with caution and may require dose adjustments.
• Patients with hepatic impairment should use with caution.

Pregnancy & Breastfeeding

Naproxen should be avoided during the third trimester of pregnancy due to the risk of premature closure of the ductus arteriosus. It is excreted in breast milk; caution is advised when administered to nursing mothers.

Key Drug Interactions

• Increased risk of gastrointestinal bleeding when used with other NSAIDs, anticoagulants, or corticosteroids.
• May reduce the antihypertensive effect of ACE inhibitors and diuretics.
• May increase plasma concentrations of lithium.

Contraindications

• Hypersensitivity to naproxen or any of its components.
• Active peptic ulcer disease.
• History of gastrointestinal bleeding or ulceration related to NSAID therapy.
• Severe renal impairment.

Common side effects

• Gastrointestinal upset, including nausea, vomiting, and dyspepsia.
• Headache.
• Dizziness.
• Rash.
• Increased risk of cardiovascular events with long-term use.

Counselling Points

• Take with food or milk to reduce gastrointestinal irritation.
• Do not exceed the recommended dose.
• Report any signs of gastrointestinal bleeding, such as black or bloody stools, to a healthcare provider.
• Avoid alcohol while taking this medication to reduce the risk of gastrointestinal side effects.