Sinora 1Mg/1Ml & 4Mg/4Ml 1 mg, 4 mg SOLUTION FOR INFUSION
Clinical Summary
Quick overview from the medicine insert
Indication
Emergency restoration of blood pressure in acute hypotension.
Dosage (summary)
Initial infusion rate: 10-20 ml/hour (0.4-0.8 mg/hour noradrenaline base).
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly patients
Pregnancy & Breastfeeding
Safety not established; may impair placental perfusion.
Key Drug Interactions
- Volatile halogen anaesthetics
- Tricyclic antidepressants
- Serotoninergic-adrenergic antidepressants
Contraindications
- Hypersensitivity to noradrenaline
- Hypotension due to hypovolaemia
Common side effects
- Tachycardia
- Headache
- Nausea
- Anxiety
Counselling Points
- Infusion should be monitored continuously
- Avoid abrupt withdrawal to prevent hypotension
Serious warnings
- Risk of extravasation leading to tissue necrosis
- Monitor blood pressure frequently
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