Ondansetron 4 Mg /2 Ml Biotech And Ondansetron 8 Mg /4 Ml Biotech 4 mg /2 ml AND 8 mg /4 ml Injection

Indication

Management of nausea and vomiting induced by chemotherapy, radiotherapy, and post-operative nausea and vomiting.

Dosage (summary)

Adults: 8 mg IV/IM before treatment; max 16 mg for highly emetogenic chemotherapy. Elderly: max 8 mg IV for patients u226575 years.

Onset of Action / Duration

Onset: 30 mins, Duration: 6-8 hours

Special Populations

• Elderly
• Renal impairment
• Hepatic impairment

Pregnancy & Breastfeeding

Contraindicated in the first 12 weeks of pregnancy and for PONV during pregnancy. Avoid breastfeeding.

Key Drug Interactions

• QT prolonging agents
• Serotonergic medicines
• Apomorphine

Contraindications

• Hypersensitivity to ondansetron
• Congenital long QT syndrome
• First 12 weeks of pregnancy

Common side effects

• Headache
• Constipation
• Dizziness
• Visual disturbances

Counselling Points

• Monitor for signs of QT prolongation
• Avoid driving until effects are known
• Report any severe side effects immediately