Ondansetron Pharmc 4 mg/2 mL & 8 mg/4 mL Solution for injection

    Ondansetron Pharmc 4 mg/2 mL & 8 mg/4 mL Solution for injection

    S4
    PDF Leaflet Revision Date: 13 March 2023

    API: Ondansetron | Company: Pharmacorp

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Management of nausea and vomiting induced by chemotherapy, radiotherapy, and post-operative.

    Dosage (summary)

    Adults: 8 mg IV/IM before treatment; max 16 mg for highly emetogenic chemotherapy. Elderly: max 8 mg IV.

    Onset of Action / Duration

    Onset: 30 mins, Duration: up to 24 hours

    Special Populations

    • Elderly
    • Renal impairment
    • Hepatic impairment

    Pregnancy & Breastfeeding

    Contraindicated in pregnancy; avoid breastfeeding.

    Key Drug Interactions

    • QT prolonging medicines
    • Apomorphine
    • Tramadol

    Contraindications

    • Hypersensitivity to ondansetron
    • Pregnancy
    • Congenital long QT syndrome

    Common side effects

    • Headache
    • Dizziness
    • Constipation
    • Visual disturbances

    Counselling Points

    • Avoid driving until effects are known
    • Monitor for signs of myocardial ischaemia
    • Use contraception during treatment

    Serious warnings

    • QT prolongation risk
    • Myocardial ischaemia
    • Serotonin syndrome
    Important Disclaimer

    The Ondansetron Pharmc 4 mg/2 mL & 8 mg/4 mL Solution for injection professional information leaflet below is the property of Pharmacorp and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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