Rayzon 40 Mg Iv/Im Powder 40 mg Powder for solution for injection.
PDF Leaflet Revision Date: 15 June 2021
Clinical Summary
Quick overview from the medicine insert
Indication
Short-term management of post-operative pain.
Dosage (summary)
Initial 40 mg IV/IM, then 20-40 mg every 6-12 hours, max 80 mg/day.
Onset of Action / Duration
Onset: 7-14 mins, Duration: 7-24 hours.
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation.
Key Drug Interactions
- Aspirin
- ACE inhibitors
- Lithium
- Warfarin
Contraindications
- Hypersensitivity to parecoxib
- Severe hepatic impairment
- Severe renal impairment
- CABG surgery
- History of gastrointestinal bleeding
- Children under 18
Common side effects
- Hypotension
- Dyspepsia
- Nausea
- Dizziness
- Insomnia
Counselling Points
- Monitor for signs of hypersensitivity.
- Avoid use in severe renal/hepatic impairment.
- Transition to oral therapy as soon as possible.
- Caution in patients with cardiovascular risk.
Serious warnings
- Cardiovascular events risk
- Gastrointestinal complications
- Severe hypotension
- Serious skin reactions
Important Disclaimer
The Rayzon 40 Mg Iv/Im Powder 40 mg Powder for solution for injection. professional information leaflet below is the property of Pfizer Laboratories and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
Healthcare Professionals Only
This content is for registered healthcare professionals
Sign in or create a free account to read the full package insert.
Free for HPCSA-registered professionals. Powered by Medinsert.
