Piperacillin/Tazobactam 2 G/0,25 G Fresenius. Piperacillin/Tazobactam 4 G/0,5 G Fresenius 2 g/0,25 g & 4 g/0,5 g Powder for solution for infusion

Piperacillin/Tazobactam 2 G/0,25 G Fresenius. Piperacillin/Tazobactam 4 G/0,5 G Fresenius 2 g/0,25 g & 4 g/0,5 g Powder for solution for infusion

S4
PDF Leaflet Revision Date: 27 May 2025


Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of systemic and local bacterial infections.

Dosage (summary)

Adults: 4 g/0.5 g every 8 hours; adjust for renal impairment.

Special Populations

  • Renal impairment
  • Elderly

Pregnancy & Breastfeeding

Safety not established; avoid breastfeeding.

Key Drug Interactions

  • Probenecid
  • Oral anticoagulants
  • Methotrexate

Contraindications

  • Allergy to piperacillin or tazobactam
  • History of hypersensitivity to beta-lactams

Common side effects

  • Diarrhoea
  • Nausea
  • Headache
  • Rash

Counselling Points

  • Report any allergic reactions
  • Monitor for signs of colitis
  • Maintain hydration during therapy

Serious warnings

  • Serious hypersensitivity reactions
  • Pseudomembranous colitis
  • Leukopenia
Important Disclaimer

The Piperacillin/Tazobactam 2 G/0,25 G Fresenius. Piperacillin/Tazobactam 4 G/0,5 G Fresenius 2 g/0,25 g & 4 g/0,5 g Powder for solution for infusion professional information leaflet below is the property of Fresenius Kabi South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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