Bendamustine 25mg & 100mg Fresenius Injection

    Bendamustine 25mg & 100mg Fresenius Injection

    S4
    PDF Leaflet Revision Date: 10 March 2025


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    First-line treatment for specific leukemias and lymphomas.

    Dosage (summary)

    100 mg/mu00b2 for CLL; 90 mg/mu00b2 for NHL with rituximab; 120-150 mg/mu00b2 for multiple myeloma.

    Special Populations

    • Hepatic impairment
    • Renal impairment
    • Elderly patients

    Pregnancy & Breastfeeding

    Contraindicated in pregnancy and lactation.

    Key Drug Interactions

    • Live vaccines
    • QT prolonging drugs

    Contraindications

    • Hypersensitivity
    • Severe hepatic impairment
    • Severe bone marrow suppression
    • Infections
    • Jaundice

    Common side effects

    • Myelosuppression
    • Infections
    • Skin reactions

    Counselling Points

    • Monitor for infections
    • Report skin reactions
    • Avoid live vaccines

    Serious warnings

    • Myelosuppression
    • Hepatitis B reactivation
    • Severe skin reactions
    Important Disclaimer

    The Bendamustine 25mg & 100mg Fresenius Injection professional information leaflet below is the property of Fresenius Kabi South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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