Tiperabex 4 g; 0,5 g Powder for solution for infusion
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of systemic and local bacterial infections.
Dosage (summary)
Adults: 4 g/0.5 g every 8 hours; Neutropenic patients: every 6 hours.
Special Populations
- Elderly
- Renal impairment
Pregnancy & Breastfeeding
Not established; contraindicated in breastfeeding.
Key Drug Interactions
- Aminoglycosides
- Anticoagulants
- Methotrexate
- Vancomycin
Contraindications
- Hypersensitivity to piperacillin/tazobactam
- History of penicillin allergy
Common side effects
- Diarrhoea
- Nausea
- Headache
- Rash
Counselling Points
- Monitor for allergic reactions
- Report severe diarrhoea
- Avoid mixing with aminoglycosides
Serious warnings
- Severe hypersensitivity reactions
- Pseudomembranous colitis
- Hemophagocytic lymphohistiocytosis
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