Colcin 0,5 mg Tablets
PDF Leaflet Revision Date: 14 December 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Relief of acute attacks of gout.
Dosage (summary)
Initial: 0.5-1 mg (1-2 tablets) immediately, then 0.5 mg every 2 hours until pain relief or side effects occur. Max: 6 mg (12 tablets) in 3 days.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- P-glycoprotein inhibitors
- CYP3A4 inhibitors
- Macrolide antibiotics
- Oral anticoagulants
Contraindications
- Hypersensitivity to colchicine
- Blood dyscrasias
- Severe renal insufficiency
- Severe hepatic insufficiency
Common side effects
- Nausea
- Vomiting
- Abdominal pain
- Diarrhoea
Counselling Points
- Avoid exceeding prescribed dose
- Report gastrointestinal symptoms
- Use effective contraception if of childbearing potential
Serious warnings
- Narrow therapeutic window
- Potentially fatal overdose
- Monitor for blood dyscrasias
Important Disclaimer
The Colcin 0,5 mg Tablets professional information leaflet below is the property of Abex Pharmaceutica and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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