Zantac 150mg & 300mg Tablet

Zantac 150mg & 300mg Tablet

S3
PDF Leaflet Revision Date: 30 September 2016


Clinical Summary

Quick overview from the medicine insert

Indication

Treatment of duodenal ulcers, gastric ulcers, reflux oesophagitis, and Zollinger-Ellison Syndrome.

Dosage (summary)

150 mg twice daily or 300 mg at bedtime; adjust for renal impairment.

Onset of Action / Duration

Onset: 1-3 hours, Duration: 6-12 hours

Special Populations

  • Elderly
  • Renal impairment

Pregnancy & Breastfeeding

Safety not established in pregnancy or lactation.

Key Drug Interactions

  • Anticoagulants (e.g., warfarin)
  • Procainamide
  • Sucralfate

Contraindications

  • Hypersensitivity to ranitidine

Common side effects

  • Headache
  • Dizziness
  • Nausea
  • Constipation

Counselling Points

  • Take before meals or at bedtime.
  • Avoid alcohol.
  • Monitor for signs of allergic reactions.

Serious warnings

  • Risk of masking gastric carcinoma
  • Increased risk of pneumonia in certain populations
Important Disclaimer

The Zantac 150mg & 300mg Tablet professional information leaflet below is the property of Glaxosmithkline South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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