Rimactazid 150/75 150mg. 75mg Tablet
Clinical Summary
Quick overview from the medicine insert
Indication
Pulmonary tuberculosis in the continuous phase of treatment.
Dosage (summary)
Rifampicin 10 mg/kg (max 600 mg), Isoniazid 5 mg/kg (max 300 mg) daily.
Special Populations
- Renal impairment
- Hepatic impairment
- Diabetes mellitus
- Chronic alcoholism
Pregnancy & Breastfeeding
Safety during pregnancy and lactation not established; caution advised.
Key Drug Interactions
- Halothane
- Ketoconazole
- Phenytoin
- Warfarin
- Oral contraceptives
Contraindications
- Hypersensitivity to rifamycins or isoniazid
- Jaundice
- Liver damage
Common side effects
- Liver dysfunction
- Nausea
- Vomiting
- Skin rashes
- Thrombocytopenia
Counselling Points
- Monitor for signs of liver damage
- Avoid alcohol
- Use non-hormonal contraceptives
Serious warnings
- Monitor liver function
- Risk of severe hepatitis
- May exacerbate convulsive disorders
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