Rimactazid 150/75 150mg. 75mg Tablet

Rimactazid 150/75 150mg. 75mg Tablet

S4
PDF Leaflet Revision Date: 02 May 2019

API: Rifampicin Isoniazid | Company: Sandoz

Clinical Summary

Quick overview from the medicine insert

Indication

Pulmonary tuberculosis in the continuous phase of treatment.

Dosage (summary)

Rifampicin 10 mg/kg (max 600 mg), Isoniazid 5 mg/kg (max 300 mg) daily.

Special Populations

  • Renal impairment
  • Hepatic impairment
  • Diabetes mellitus
  • Chronic alcoholism

Pregnancy & Breastfeeding

Safety during pregnancy and lactation not established; caution advised.

Key Drug Interactions

  • Halothane
  • Ketoconazole
  • Phenytoin
  • Warfarin
  • Oral contraceptives

Contraindications

  • Hypersensitivity to rifamycins or isoniazid
  • Jaundice
  • Liver damage

Common side effects

  • Liver dysfunction
  • Nausea
  • Vomiting
  • Skin rashes
  • Thrombocytopenia

Counselling Points

  • Monitor for signs of liver damage
  • Avoid alcohol
  • Use non-hormonal contraceptives

Serious warnings

  • Monitor liver function
  • Risk of severe hepatitis
  • May exacerbate convulsive disorders
Important Disclaimer

The Rimactazid 150/75 150mg. 75mg Tablet professional information leaflet below is the property of Sandoz and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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