Etoposide-Hexal 50mg / 2.5ml. 100mg / 5ml. 200mg / 10ml. 400mg / 20ml. 1000mg / 50ml Infusion

    Etoposide-Hexal 50mg / 2.5ml. 100mg / 5ml. 200mg / 10ml. 400mg / 20ml. 1000mg / 50ml Infusion

    S4
    PDF Leaflet Revision Date: 29 June 2019

    API: Etoposide | Company: Sandoz

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Management of testicular and small cell lung tumors.

    Dosage (summary)

    IV: 50-100 mg/mu00b2/day for 5 days or 100 mg/mu00b2 on days 1, 3, 5 every 3-4 weeks.

    Special Populations

    • Renal impairment
    • Hepatic impairment

    Pregnancy & Breastfeeding

    Can cause fetal harm; effective contraception required during treatment.

    Key Drug Interactions

    • Ciclosporin
    • Cisplatin
    • Phenytoin
    • Warfarin

    Contraindications

    • Hypersensitivity to etoposide
    • Severe hepatic dysfunction
    • Bone marrow depression
    • Renal impairment

    Common side effects

    • Myelosuppression
    • Leukopenia
    • Thrombocytopenia
    • Anaphylactic reactions
    • Nausea

    Counselling Points

    • Monitor for signs of infection
    • Avoid live vaccines
    • Report any bleeding or bruising

    Serious warnings

    • Severe myelosuppression
    • Risk of anaphylaxis
    • Tumor lysis syndrome
    Important Disclaimer

    The Etoposide-Hexal 50mg / 2.5ml. 100mg / 5ml. 200mg / 10ml. 400mg / 20ml. 1000mg / 50ml Infusion professional information leaflet below is the property of Sandoz and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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