Sertra Tablets 50 Mg 50 mg Tablet
Clinical Summary
Quick overview from the medicine insert
Indication
Major depressive disorder, OCD, panic disorder.
Dosage (summary)
Starting dose 50 mg daily; may titrate to 150-200 mg for difficult cases.
Onset of Action / Duration
Onset: 7 days, Duration: 24 hours
Special Populations
- Elderly
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Not established; avoid breastfeeding.
Key Drug Interactions
- MAOIs
- Pimozide
- Lithium
- CNS depressants
Contraindications
- Hypersensitivity to sertraline
- MAOI use
- Children < 18 with OCD and depression
Common side effects
- Insomnia
- Dizziness
- Nausea
- Dry mouth
- Sexual dysfunction
Counselling Points
- Monitor for worsening depression
- Avoid alcohol
- Taper off to discontinue
Serious warnings
- Serotonin syndrome
- QTc prolongation
- Suicidal thoughts
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