Salazopyrin 500 Mg Tablets 500 mg Tablets
PDF Leaflet Revision Date: 17 October 2025
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of acute ulcerative colitis and Crohn's disease.
Dosage (summary)
Adults: 2-4 tablets every 6 hours (max 24 tablets/day) for acute; 4 tablets/day for remission.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation due to potential teratogenicity.
Key Drug Interactions
- Increased risk of leukopenia with thiopurines
- Potentiation of anticoagulants
- Reduced absorption of folate
Contraindications
- Hypersensitivity to sulphasalazine
- Porphyria
- Severe renal or hepatic failure
- Gastric and duodenal ulcers
Common side effects
- Gastric distress
- Nausea
- Leukopenia
- Pruritus
Counselling Points
- Monitor for signs of infection
- Report any rash or hypersensitivity symptoms
- Maintain adequate hydration to prevent crystalluria
Serious warnings
- Risk of serious infections
- Myelosuppression
- Severe hypersensitivity reactions
Important Disclaimer
The Salazopyrin 500 Mg Tablets 500 mg Tablets professional information leaflet below is the property of Pfizer Laboratories and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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