Amtas 5mg or 10mg Tablets
PDF Leaflet Revision Date: 23 June 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of hypertension and angina pectoris.
Dosage (summary)
Initial dose 5 mg once daily, may increase to 10 mg.
Special Populations
- Elderly
- Hepatic impairment
- Renal failure
Pregnancy & Breastfeeding
Safety in pregnancy and breastfeeding not established; use caution.
Key Drug Interactions
- CYP3A4 inhibitors
- Grapefruit juice
- Simvastatin
Contraindications
- Severe hypotension
- Shock
- Aortic stenosis
- Heart failure
Common side effects
- Dizziness
- Headache
- Palpitations
- Nausea
- Oedema
Counselling Points
- Monitor blood pressure regularly
- Avoid grapefruit juice
- Caution when driving or operating machinery
Serious warnings
- Caution in hypertensive crisis
- Risk of hypotension with CYP3A4 inhibitors
Important Disclaimer
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