Aranesp Injection

    Aranesp Injection

    S4
    PDF Leaflet Revision Date: 07 October 2020


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Treatment of symptomatic anaemia in chronic renal failure and cancer patients receiving chemotherapy.

    Dosage (summary)

    Initial dose: 0.45 u03bcg/kg once weekly or 0.75 u03bcg/kg every two weeks; adjust based on haemoglobin response.

    Special Populations

    • Renal impairment
    • Hepatic impairment

    Pregnancy & Breastfeeding

    Caution in pregnancy; unknown if excreted in breast milk.

    Key Drug Interactions

    • Ciclosporin
    • Tacrolimus

    Contraindications

    • Hypersensitivity
    • Poorly controlled hypertension

    Common side effects

    • Hypertension
    • Stroke
    • Thromboembolic events
    • Convulsions
    • Allergic reactions

    Counselling Points

    • Monitor for signs of allergic reactions
    • Rotate injection sites
    • Report any unusual symptoms immediately

    Serious warnings

    • Increased risk of death and serious cardiovascular events
    • Monitor blood pressure
    • Avoid haemoglobin > 12 g/dl
    Important Disclaimer

    The Aranesp Injection professional information leaflet below is the property of Amgen South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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