Aspen Colchicine Ds 1mg Tablet
PDF Leaflet Revision Date: 26 November 2015
Clinical Summary
Quick overview from the medicine insert
Indication
Emergency treatment of acute attacks of gout.
Dosage (summary)
1 mg initially, then 0.5 mg every 2 hours, max 6 mg.
Onset of Action / Duration
Onset: 0.5-2 hours, Duration: 3-7 days between courses.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; use with caution in breastfeeding.
Key Drug Interactions
- CYP3A4 inhibitors
- P-glycoprotein inhibitors
- Oral anticoagulants
Contraindications
- Hypersensitivity
- Severe renal impairment
- Haemodialysis
- Blood disorders
Common side effects
- Nausea
- Vomiting
- Diarrhoea
- Abdominal pain
- Alopecia
Counselling Points
- Monitor for gastrointestinal side effects
- Avoid alcohol
- Report muscle pain or weakness
Serious warnings
- Fatal overdoses reported
- Myelosuppression risk
- Neuromuscular toxicity
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