Kolcrys 0,5 mg Tablets
PDF Leaflet Revision Date: 29 March 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Relief of acute attacks of gout.
Dosage (summary)
Initial: 0.5-1 mg orally, then 0.5 mg every 2 hours until relief or GI symptoms occur. Max: 6 mg in 3 days.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly patients
Pregnancy & Breastfeeding
Contraindicated in pregnancy; use with caution during breastfeeding.
Key Drug Interactions
- Macrolides
- Calcium channel antagonists
- CYP3A4 inhibitors
- P-glycoprotein inhibitors
Contraindications
- Hypersensitivity to colchicine
- Pregnancy
- Severe renal impairment
- Severe hepatic impairment
- Blood disorders
- Patients undergoing haemodialysis
Common side effects
- Nausea
- Vomiting
- Diarrhoea
- Abdominal pain
- Myopathy
- Rhabdomyolysis
Counselling Points
- Do not exceed recommended dose
- Report any signs of toxicity immediately
- Avoid grapefruit juice
Serious warnings
- Potentially toxic; narrow therapeutic window
- Risk of cumulative toxicity in elderly and debilitated patients
Important Disclaimer
The Kolcrys 0,5 mg Tablets professional information leaflet below is the property of Forrester Pharma and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
Healthcare Professionals Only
This content is for registered healthcare professionals
Sign in or create a free account to read the full package insert.
Free for HPCSA-registered professionals. Powered by Medinsert.
