Avastin 100 mg & 400 mg Solution
PDF Leaflet Revision Date: 19 April 2022
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of various cancers including colorectal, breast, lung, renal, ovarian, cervical, and glioblastoma.
Dosage (summary)
5-15 mg/kg IV every 2-3 weeks depending on cancer type.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; avoid breastfeeding during treatment and for 6 months after.
Key Drug Interactions
- Sunitinib
- Chemotherapy agents
Contraindications
- Hypersensitivity to bevacizumab
- Pregnancy
- Breastfeeding
- Concomitant use with sunitinib
Common side effects
- Hypertension
- Fatigue
- Diarrhoea
- Abdominal pain
Counselling Points
- Monitor blood pressure
- Report signs of bleeding
- Discuss fertility preservation options
Serious warnings
- Gastrointestinal perforations
- Wound healing complications
- Hypertension
- Arterial thromboembolism
Important Disclaimer
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