Combigan 2 mg/ml + 5 mg/ml Ophthalmic solution

    Combigan 2 mg/ml + 5 mg/ml Ophthalmic solution

    S3
    PDF Leaflet Revision Date: 17 February 2025

    API: Brimonidine Tartrate | Company: AbbVie

    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Control of intraocular pressure in chronic open-angle glaucoma or ocular hypertension.

    Dosage (summary)

    One drop in affected eye(s) twice daily, 12 hours apart.

    Special Populations

    • Renal impairment
    • Hepatic impairment

    Pregnancy & Breastfeeding

    Not recommended during pregnancy or breastfeeding.

    Key Drug Interactions

    • MAO inhibitors
    • CNS depressants
    • Beta-blockers

    Contraindications

    • Hypersensitivity
    • Reactive airway disease
    • Severe cardiac conditions
    • Patients under 18 years

    Common side effects

    • Conjunctival hyperaemia
    • Burning sensation
    • Bradycardia
    • Somnolence

    Counselling Points

    • Avoid contact with the eye tip
    • Remove contact lenses before use
    • Monitor for allergic reactions

    Serious warnings

    • Respiratory and cardiac reactions
    • Caution in patients with asthma
    • Potential for systemic absorption
    Important Disclaimer

    The Combigan 2 mg/ml + 5 mg/ml Ophthalmic solution professional information leaflet below is the property of AbbVie and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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