Cyclocord 500 Mg & 1G 500 mg, 1 g Powder for solution for injection/infusion
Clinical Summary
Quick overview from the medicine insert
Indication
Active treatment of neoplastic diseases and progressive autoimmune diseases.
Dosage (summary)
Administered by experienced oncologists; max 50 mg/kg body mass; adjust based on patient response.
Special Populations
- Hepatic impairment
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in first trimester; avoid breastfeeding during treatment.
Key Drug Interactions
- Aprepitant
- Busulfan
- Ciprofloxacin
- Azole-antimycotics
- Warfarin
Contraindications
- Hypersensitivity to cyclophosphamide
- Severe bone marrow suppression
- Cystitis
- Infections
Common side effects
- Myelosuppression
- Nausea
- Vomiting
- Alopecia
- Infections
Counselling Points
- Avoid pregnancy during treatment
- Use effective contraception
- Monitor for infections
- Stay hydrated
Serious warnings
- Anaphylactic reactions
- Myelosuppression
- Urotoxicity
- Cardiotoxicity
- Pulmonary toxicity
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