Cymevene 500mg Freeze dried powder
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment and prevention of cytomegalovirus disease in immunocompromised patients u2265 12 years.
Dosage (summary)
Induction: 5 mg/kg every 12 hours for 14-21 days; Maintenance: 5 mg/kg once daily.
Special Populations
- Renal impairment
- Elderly population
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; potential teratogenic effects.
Key Drug Interactions
- Imipenem-cilastatin
- Zidovudine
- Didanosine
Contraindications
- Pregnancy
- Lactation
- Hypersensitivity to ganciclovir
- Neutropenia
- Thrombocytopenia
Common side effects
- Neutropenia
- Anaemia
- Thrombocytopenia
- Visual impairment
- Dizziness
Counselling Points
- Monitor blood counts regularly
- Use effective contraception
- Avoid rapid IV injection
Serious warnings
- Myelosuppression
- Potential teratogenicity
- Cross hypersensitivity with aciclovir
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