Trepiline 10 mg, 25 mg Tablets
PDF Leaflet Revision Date: 28 July 2017
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of depression in patients 18 years and older.
Dosage (summary)
Initial: 75-150 mg daily; Maintenance: 50-100 mg daily.
Onset of Action / Duration
Onset: 6 hours, Duration: 9-25 hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not established; contraindicated in pregnancy and lactation.
Key Drug Interactions
- MAOIs
- CNS depressants
- Antihypertensives
- SSRIs
Contraindications
- Hypersensitivity
- Myocardial infarction
- Concurrent MAOIs
- Pregnancy
- Children under 18
Common side effects
- Drowsiness
- Dry mouth
- Constipation
- Blurred vision
Counselling Points
- Avoid driving until effects are known
- Monitor for suicidal thoughts
- Do not combine with alcohol or CNS depressants
Serious warnings
- Suicidal tendencies
- Cardiac disease caution
- Anticholinergic effects
Important Disclaimer
The Trepiline 10 mg, 25 mg Tablets professional information leaflet below is the property of Pharmacare Limited and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
Healthcare Professionals Only
This content is for registered healthcare professionals
Sign in or create a free account to read the full package insert.
Free for HPCSA-registered professionals. Powered by Medinsert.
