Diprivan 10mg/ml Injection /
PDF Leaflet Revision Date: 07 March 2003
Clinical Summary
Quick overview from the medicine insert
Indication
Induction and maintenance of general anaesthesia.
Dosage (summary)
Induction: 1.5-2.5 mg/kg; Maintenance: 4-12 mg/kg/hr.
Onset of Action / Duration
Onset: 30 secs, Duration: 6-8 hours
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Not recommended in pregnancy; safety in lactation not established.
Key Drug Interactions
- Narcotics
- Benzodiazepines
- Neuromuscular blockers
Contraindications
- Hypersensitivity to propofol
- Children under 3 years
- Croup or epiglottitis
Common side effects
- Hypotension
- Apnoea
- Nausea
- Vomiting
Counselling Points
- Monitor for respiratory depression
- Avoid skilled tasks post-anesthesia
- Use aseptic technique during administration
Serious warnings
- Respiratory depression
- Anaphylactic reactions
- Cardiovascular depression
Important Disclaimer
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