Dirento Sr 150 Mg 150 mg Sustained-release tablet
PDF Leaflet Revision Date: 2 May 2023
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of depression.
Dosage (summary)
Initial: 150 mg once daily; max: 300 mg/day (twice daily if >150 mg).
Special Populations
- Hepatic impairment
- Renal impairment
- Elderly
Pregnancy & Breastfeeding
Safety not established; avoid breastfeeding.
Key Drug Interactions
- CYP2B6 inhibitors
- CYP2D6 substrates
- Levodopa
- Alcohol
Contraindications
- Hypersensitivity to bupropion
- Seizure disorder
- Bulimia or anorexia nervosa
- Severe hepatic cirrhosis
- Concomitant MAOIs
Common side effects
- Insomnia
- Agitation
- Anxiety
- Dry mouth
- Headache
Counselling Points
- Avoid alcohol
- Monitor for mood changes
- Do not crush or chew tablets
Serious warnings
- Risk of seizures
- Suicidal ideation
- Caution in hepatic impairment
Important Disclaimer
The Dirento Sr 150 Mg 150 mg Sustained-release tablet professional information leaflet below is the property of Trinity Pharma and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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