Docetaxel Teva 20 mg, 80 mg Concentrate for solution for infusion
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of various cancers including breast, lung, ovarian, prostate, and head and neck cancers.
Dosage (summary)
75-100 mg/mu00b2 every 3 weeks, depending on cancer type and treatment regimen.
Onset of Action / Duration
Onset: 30 mins, Duration: 6-8 hours
Special Populations
- Hepatic impairment
- Elderly
- Renal impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy; breastfeeding should be discontinued during therapy.
Key Drug Interactions
- Strong CYP3A4 inhibitors
- Dexamethasone
- Prednisone
Contraindications
- Hypersensitivity to docetaxel
- Baseline neutrophil count < 1500 cells/mmu00b3
- Severe liver impairment
Common side effects
- Neutropenia
- Alopecia
- Nausea
- Vomiting
- Stomatitis
Counselling Points
- Monitor for signs of infection
- Avoid pregnancy
- Report any severe side effects immediately
Serious warnings
- Severe hypersensitivity reactions
- Fluid retention
- Potential for second primary malignancies
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