Docetaxel Zydus 20 / 80 20mg / 80mg Solution for infusion.
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of various cancers including breast, lung, ovarian, prostate, head and neck, and gastric cancers.
Dosage (summary)
75-100 mg/mu00b2 every 3 weeks, depending on cancer type and treatment regimen.
Onset of Action / Duration
Onset: 30 mins, Duration: 3 weeks
Special Populations
- Hepatic impairment
- Elderly patients
- Children
Pregnancy & Breastfeeding
Contraindicated; teratogenic in animals.
Key Drug Interactions
- CYP3A4 inhibitors
- Ciclosporin
- Tacrolimus
Contraindications
- Hypersensitivity to docetaxel
- Neutrophil count < 1500 cells/mmu00b3
- Severe liver impairment
Common side effects
- Neutropenia
- Hypersensitivity reactions
- Fluid retention
- Diarrhea
- Nausea
Counselling Points
- Monitor for signs of infection
- Avoid pregnancy during treatment
- Report any severe side effects immediately
Serious warnings
- Severe hypersensitivity reactions
- Fluid retention
- Respiratory disorders
- Cardiac toxicity
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