Taxocan 20 / 80 20 mg & 80 mg Solution for infusion
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of various cancers including breast, lung, ovarian, prostate, head and neck, and gastric cancers.
Dosage (summary)
75 mg/mu00b2 every 3 weeks for breast cancer; 100 mg/mu00b2 for monotherapy; adjust based on combination therapy.
Onset of Action / Duration
Onset: 30 mins, Duration: 3 weeks
Special Populations
- Hepatic impairment
- Elderly patients
- Children
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation due to teratogenic effects.
Key Drug Interactions
- CYP3A4 inhibitors
- Ciclosporin
- Tacrolimus
Contraindications
- Hypersensitivity to docetaxel
- Neutrophil count < 1500 cells/mmu00b3
- Severe liver impairment
Common side effects
- Neutropenia
- Hypersensitivity reactions
- Fluid retention
- Diarrhea
- Nausea
Counselling Points
- Monitor for signs of infection
- Avoid pregnancy during treatment
- Report any severe side effects immediately
Serious warnings
- Severe hypersensitivity reactions
- Fluid retention
- Increased risk of infections
- Cardiac dysrhythmias
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