Dorik Tablets 200 mg TABLET
PDF Leaflet Revision Date: 26 February 2021
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of chronic hepatitis C in adults, in combination with peginterferons.
Dosage (summary)
1000 mg daily for <75 kg or 1200 mg for >75 kg, divided doses with food.
Special Populations
- Renal impairment
- Hepatic impairment
- Elderly patients (> 65 years)
Pregnancy & Breastfeeding
Contraindicated in pregnancy; requires effective contraception during and 6 months post-treatment.
Key Drug Interactions
- Antacids may decrease bioavailability
- Monitor HIV RNA levels with zidovudine or stavudine
Contraindications
- Pregnancy
- Severe renal impairment (C cr < 50 ml/min)
- Severe hepatic impairment
- Hypersensitivity
- Haemoglobinopathies
Common side effects
- Anaemia
- Depression
- Fatigue
- Nausea
- Palpitations
Counselling Points
- Use two forms of contraception
- Monitor for signs of anaemia
- Avoid pregnancy during and after treatment
Serious warnings
- Monotherapy not effective for hepatitis C
- Risk of severe anaemia
- Teratogenic effects
Important Disclaimer
The Dorik Tablets 200 mg TABLET professional information leaflet below is the property of Aurogen South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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