Eno Active Fruit Salt Regular 5.0g Powder
Clinical Summary
Quick overview from the medicine insert
Indication
Fast relief of indigestion and heartburn; urinary alkaliniser.
Dosage (summary)
Adults: 5 ml or 1 sachet in water; max 2 doses every 2-3 hours, max 14 days.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safety in pregnancy and lactation not established.
Key Drug Interactions
- Increased renal clearance of acidic medicines
- Decreased renal clearance of basic medicines
- Enhances lithium excretion
Contraindications
- Hypersensitivity
- Hypertension
- Heart failure
- Cirrhosis
- Metabolic alkalosis
- Hypocalcaemia
- Hypochlorhydria
Common side effects
- Flatulence
- Stomach cramps
- Abdominal distension
Counselling Points
- Do not exceed recommended dose
- Consult a doctor if discomfort persists
- Avoid use in sodium-restricted diets
Serious warnings
- Use with care in renal insufficiency
- May cause metabolic alkalosis
- Excessive use may lead to sodium overloading
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Clinical Particulars
Section 4 of the official insert — extracted exactly as issued, no alterations
4.1 Therapeutic indications
As an antacid: e.g. for the fast relief of indigestion and heartburn.
As a urinary alkaliniser
4.2 Posology and method of administration
As an antacid:
ADULTS: One 5 ml medicine measure or one sachet in a glass of water. A second dose may be taken after 2-3 hours. Minimum dosing interval: 2 hours Maximum daily dose (MDD): 2 x 5 ml medicine measures or 2 sachets. Maximum duration of antacid use at MDD: 14 days.
As a urinary alkaliniser:
ADULTS: One 5 ml medicine measure or one sachet well diluted with water to be taken after meals morning and evening.
4.3 Contraindications
Hypersensitivity to any of the ingredients of ENO ACTIVE FRUIT SALTS, including excipients. Avoid use if suffering from hypertension, heart failure or cirrhosis of the liver and in patients with impaired hepatic and renal failure. ENO ACTIVE FRUIT SALTS should not be administered to patients with metabolic or respiratory alkalosis, hypocalcaemia or hypochlorhydria. Should not be given with urinary antiseptics which require an acid urine, such as methenamine mandelate and methenamine hippurate.
4.4 Special warnings and precautions for use
Use with care in patients suffering from oedema and renal insufficiency. ENO ACTIVE FRUIT SALTS does not eradicate bacteriuria, although they may temporarily relieve lower urinary tract symptoms. Do not use in patients with congestive heart failure or hypertension except under the advice and supervision of a doctor. Not to be used excessively. If there is persistent discomfort, a doctor should be consulted.
Citric acid ingested frequently or in large quantities may cause erosion of the teeth and local irritation. Excessive doses may lead to sodium overloading and hyperosmolality. Contains sodium. Persons on a sodium-restricted diet should not take multiple doses of ENO ACTIVE FRUIT SALTS unless directed by a doctor. Excessive administration may lead to metabolic alkalosis especially in patients with impaired renal function.
4.5 Interactions with other medicines
ENO ACTIVE FRUIT SALTS may interact with many medicines, affecting the rate and/or extent of their absorption. Sodium bicarbonate administration leads to alkalinisation of the urine resulting in increased renal clearance of acidic medicines, or decreased renal clearance of basic medicines which may result in toxicity. Sodium bicarbonate enhances lithium excretion.
4.6 Fertility, pregnancy and lactation
Safety in pregnancy and lactation has not been established.
4.7 Effects on ability to drive and use machines
No significant effect on the ability to perform task that require judgement, motor, or cognitive skills.
4.8 Undesirable effects
Frequencies of the following side effects are unknown.
Gastrointestinal disorders: Flatulence, stomach cramps, abdominal distension. Citric acid ingested frequently or in large quantities may cause erosion of the teeth and local irritation. Not to be used excessively. If there is persistent discomfort, consult a doctor.
Metabolic disorders: Excessive administration may lead to metabolic alkalosis especially in patients with impaired renal function. Symptoms may include shortness of breath, muscle weakness and mental disturbances such as restlessness, convulsions and coma. Muscle hypertonicity, twitching and tetany may develop especially in hypocalcaemic patients. (See WARNINGS AND SPECIAL PRECAUTIONS)
4.9 Overdose
See SIDE EFFECTS Excessive administration of sodium bicarbonate may lead to metabolic alkalosis. Treatment is supportive and symptomatic and consists mainly of correction of fluid and electrolyte balance. A doctor should be consulted in known cases of overdosage.