Glucophage XR 500mg. 750mg. 1000mg Tablet
PDF Leaflet Revision Date: 27 November 2014
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of type 2 diabetes mellitus in adults.
Dosage (summary)
Starting dose: 500 mg once daily with evening meal; max: 2000 mg daily.
Onset of Action / Duration
Onset: 5 hours, Duration: 24 hours
Special Populations
- Elderly
- Renal impairment
Pregnancy & Breastfeeding
Not advised during pregnancy; unknown safety in lactation.
Key Drug Interactions
- Alcohol
- Iodinated contrast agents
- Glucocorticoids
- Sulphonylureas
Contraindications
- Hypersensitivity to metformin
- Diabetic ketoacidosis
- Renal failure
- Hepatic insufficiency
Common side effects
- Nausea
- Vomiting
- Diarrhoea
- Abdominal pain
- Taste disturbance
Counselling Points
- Take with food
- Monitor blood glucose regularly
- Avoid alcohol
- Report symptoms of lactic acidosis
Serious warnings
- Risk of lactic acidosis
- Monitor renal function
- Discontinue before surgery
Important Disclaimer
The Glucophage XR 500mg. 750mg. 1000mg Tablet professional information leaflet below is the property of Merck and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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