Hy-Po-Tone 250 mg, 500 mg Film-coated tablet
PDF Leaflet Revision Date: 01 March 2013
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of essential hypertension.
Dosage (summary)
250 mg two or three times daily; usual dose 500 mg to 2 g daily.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safety in pregnancy not established; crosses placenta. Small amounts in breast milk.
Key Drug Interactions
- Lithium
- Sympathomimetics
- Tricyclic antidepressants
- MAOIs
Contraindications
- Hypersensitivity to methyldopa
- Impaired kidney or liver function
- Mental depression
- Acute liver disease
- Phaeochromocytoma
- Porphyria
Common side effects
- Headache
- Drowsiness
- Oedema
- Nausea
- Diarrhoea
Counselling Points
- Monitor for signs of liver toxicity
- Avoid activities requiring alertness if drowsy
- Report any unexplained fever
Serious warnings
- Periodic blood counts and liver function tests advised
- May cause sedation
- Severe hypotension during anaesthesia
Important Disclaimer
The Hy-Po-Tone 250 mg, 500 mg Film-coated tablet professional information leaflet below is the property of Pharmacare Limited and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
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