Inechol 10/10 mg, 10/20 mg, 10/40 mg Tablets

    Inechol 10/10 mg, 10/20 mg, 10/40 mg Tablets

    S4
    PDF Leaflet Revision Date: 09 November 2023


    Clinical Summary

    Quick overview from the medicine insert

    Indication

    Adjunctive therapy for primary hypercholesterolaemia and HoFH.

    Dosage (summary)

    Starting dose: 10/20 mg/day; max: 10/80 mg/day.

    Special Populations

    • Elderly
    • Hepatic impairment
    • Renal impairment

    Pregnancy & Breastfeeding

    Contraindicated in pregnancy and lactation.

    Key Drug Interactions

    • CYP3A4 inhibitors
    • Fibrates
    • Ciclosporin
    • Danazol

    Contraindications

    • Hypersensitivity
    • Active liver disease
    • Moderate to severe hepatic impairment
    • Pregnancy
    • Lactation
    • Children

    Common side effects

    • Headache
    • Abdominal pain
    • Diarrhoea
    • Myopathy
    • Rhabdomyolysis

    Counselling Points

    • Take in the evening
    • Avoid grapefruit juice
    • Report muscle pain or weakness

    Serious warnings

    • Risk of myopathy/rhabdomyolysis
    • Monitor liver enzymes
    • Caution in alcohol use
    Important Disclaimer

    The Inechol 10/10 mg, 10/20 mg, 10/40 mg Tablets professional information leaflet below is the property of Viatris South Africa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>

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