Klaryvid 250 mg. 500 mg. FC tablets.
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of mild to moderate severe infections.
Dosage (summary)
Adults: 250 mg twice daily; severe infections: 500 mg twice daily.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Safety in pregnancy not established; excreted in breast milk.
Key Drug Interactions
- Ergot alkaloids
- Oral midazolam
- Statins (lovastatin, simvastatin)
- Colchicine
Contraindications
- Hypersensitivity to macrolides
- QT prolongation history
- Severe hepatic failure
Common side effects
- Nausea
- Diarrhea
- Headache
- Rash
Counselling Points
- Take with or without food
- Monitor for signs of liver dysfunction
- Avoid alcohol
Serious warnings
- QT prolongation risk
- Hepatic dysfunction
- Pseudomembranous colitis
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