Lavem 300 mg Tablets
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of HIV-1 infection in adults aged 18 years and older.
Dosage (summary)
One tablet orally once daily, without regard to food.
Special Populations
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and lactation; neural tube defects reported.
Key Drug Interactions
- Rifampicin decreases dolutegravir levels
- Metformin contraindicated
Contraindications
- Hypersensitivity to components
- Renal impairment
- Pregnancy
- Lactation
- Moderate and severe hepatic impairment
Common side effects
- Headache
- Nausea
- Fatigue
- Rash
- Dizziness
Counselling Points
- Take once daily without food
- Use effective contraception
- Monitor for signs of lactic acidosis
Serious warnings
- Lactic acidosis
- Severe hepatomegaly
- Risk of opportunistic infections
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