Linobact Iv 600 mg/300 ml Solution for infusion.
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of infections caused by susceptible Gram-positive bacteria.
Dosage (summary)
600 mg IV every 12 hours for adults; 10 mg/kg IV every 8 hours for children.
Special Populations
- Elderly
- Renal impairment
- Hepatic impairment
Pregnancy & Breastfeeding
Contraindicated in pregnancy and breastfeeding.
Key Drug Interactions
- Serotonergic drugs
- Monoamine oxidase inhibitors
- Sympathomimetics
Contraindications
- Hypersensitivity to linezolid
- Uncontrolled hypertension
- Carcinoid syndrome
Common side effects
- Headache
- Diarrhoea
- Nausea
- Vomiting
- Metallic taste
Counselling Points
- Monitor for signs of serotonin syndrome
- Avoid tyramine-rich foods
- Report visual changes immediately
Serious warnings
- Pseudomembranous colitis
- Myelosuppression
- Peripheral neuropathy
- Lactic acidosis
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