Lomanor 5 Mg And 10 Mg 5 mg.10 mg Tablet.
Clinical Summary
Quick overview from the medicine insert
Indication
Treatment of hypertension and angina pectoris.
Dosage (summary)
Initial dose 5 mg once daily, may increase to 10 mg after 10-14 days.
Onset of Action / Duration
Onset: 6-12 hours, Duration: 24 hours
Special Populations
- Elderly
- Hepatic impairment
- Renal failure
Pregnancy & Breastfeeding
Safety in pregnancy and lactation not established.
Key Drug Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
- Simvastatin
- Grapefruit juice
Contraindications
- Hypersensitivity to dihydropyridines or amlodipine
- Concomitant use with grapefruit juice
Common side effects
- Dizziness
- Headache
- Palpitations
- Abdominal pain
- Flushing
Counselling Points
- Monitor for dizziness and hypotension.
- Avoid grapefruit juice.
- Report any severe side effects.
Serious warnings
- Risk of hypotension with CYP3A4 inhibitors
- Increased reports of pulmonary oedema in heart failure patients
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