Macleods Efavirenz 600 mg Tablets
PDF Leaflet Revision Date: 13 June 2023
Clinical Summary
Quick overview from the medicine insert
Indication
For treatment of HIV-1 in combination with other antiretroviral agents.
Dosage (summary)
600 mg orally, once daily, preferably at bedtime on an empty stomach.
Special Populations
- Hepatic impairment
- Renal impairment
- Elderly patients
Pregnancy & Breastfeeding
May cause fetal harm; contraindicated in pregnancy. Not recommended during breastfeeding.
Key Drug Interactions
- CYP3A4 inducers/inhibitors
- Rifampicin
- St John's wort
Contraindications
- Hypersensitivity to efavirenz
- Severe hepatic impairment
- Weight < 40 kg
Common side effects
- Rash
- Dizziness
- Nausea
- Headache
- Fatigue
Counselling Points
- Take on an empty stomach
- Avoid high-fat meals
- Use barrier contraception
Serious warnings
- Serious psychiatric symptoms
- Risk of liver injury
- Immune Reconstitution Inflammatory Syndrome
Important Disclaimer
The Macleods Efavirenz 600 mg Tablets professional information leaflet below is the property of Macleods Pharmaceuticals Sa and is provided on Medinsert exactly as issued, with no.. alterations or editorial changes. We make every effort to keep content current by updating documents as soon as new versions become available. Medinsert serves as a trusted access point for healthcare professionals, but does not replace official sources or clinical judgement. For more details, please read our full disclaimer. read more>>
Healthcare Professionals Only
This content is for registered healthcare professionals
Sign in or create a free account to read the full package insert.
Free for HPCSA-registered professionals. Powered by Medinsert.
